Borderline hypertension was defined as anĪverage systolic pressure between 140 and 160 mm Hg with an average diastolic Hyper tension: (a) 11 with borderline hypertension, (b) 8 with systolic hypertension,Īnd (c) 31 with diastolic hypertension. The 50 patients were divided into 3 groups, according to the degree of pre-treatment Included are data on theĮffect of such therapy on one parameter of cardiac funct(ion in the hypertensive patient, namely, the cardiac index as measured by the external counting Subdivided into 3 groups according to the presumed severity of hypertension,Īnd maintained with antihypertensive therapy. This paper is a report of observations made on 50 hypertensive patients, Manifestations otherwise expected in untreated patients.
Natural history of the disease in each of these subgroups, so that any therapeutic alteration can be detected, i.e., disappearance or slowing of the clinical Patients into more discrete and homogeneous groups and 2) definition of the Under treatment, best established by further subdivision of hypertensive Therefore, the two crucial points to be emphasized in the evaluation ofĪntihypertensive therapy are: 1) clarification of the type of hypertension Indeed, there is a dearth of substantial information concerning the natural history of either treated or untreated hypertension. Little information on the influence of such drugs on the progression of the Relatively short periods of treatment (a few weeks or months). Judged by a measurable drop in the systolic and diastolic blood pressure after The effectiveness of the therapy has generally been Unfortunately, there has seldom been any attempt to define more closely the type of
Many reports have appeared during the past several years concerning theĮffect of various types of antihypertensive drugs on hypertension. EFFECT OF ANTIHYPERTENSIVE (PARGYLINE HYDROCHLORIDEMETHYCLOTHIAZIDE) THERAPY IN THREE TYPES OF